Our Technology

Earlier Answers for Time-Sensitive Infectious Diseases

Zepto's MDx Platform

The first targeted liquid biopsy platform for infectious diseases
Built on Nobel Prize-winning Giant Magnetoresistance (GMR) biosensor technology, Zepto combines high sensitivity, rapid turnaround, and scalable multiplexing to deliver actionable diagnostic answers when time matters most.
*This device has not been evaluated, cleared or approved for use by the FDA, and is not for sale in the U.S.

Earlier Detection

Targeted approach optimized for high sensitivity, designed to provide actionable clarity when invasive fungal infections are first suspected

Direct From Plasma

Organism ID from a simple blood sample by detecting circulating microbial cfDNA

Sample-to-Result

Load plasma sample, start run, and receive results in under 90 minutes

The Problem with IFIs

Time Matters in Invasive Fungal Infections (IFI)

3.7 Million

deaths attributed to IFIs each year worldwide

$6.7 Billion

in direct medical costs are associated with IFIs

~20 Million

people at high risk for IFIs in the U.S. alone

In immunocompromised patients, invasive fungal infections and invasive molds in particular are among the hardest infections to diagnose. Rapid pathogen identification helps guide antifungal therapy, but conventional testing is often slow or non-specific and often requires bronchoscopy or biopsy that can be delayed or unsafe.
While teams wait, hospitals incur avoidable costs: longer LOS, repeat diagnostics, and escalation of care.

Emily Rayens, Karen A Norris, Prevalence and Healthcare Burden of Fungal Infections in the United States, 2018, Open Forum Infectious Diseases, Volume 9, Issue 1, January 2022.

Zepto FungiFlex® Mold Panel

Targets the organisms responsible for >95% of invasive mold infections in a single test

Panel Targets

  • Aspergillus flavus
  • Aspergillus fumigatus
  • Aspergillus niger
  • Aspergillus terreus
  • Fusarium spp.
    • Fusarium verticillioides
    • Fusarium oxysporum
    • Fusarium solani
  • Scedosporium
    • Scedosporium spp.
    • Lomentospora prolificans
  • Mucorales agents
    • Mucor circinelloides
    • Rhizomucor miehei
    • Rhizopus microsporus
    • Rhizopus oryzae
    • Cunninghamella bertholletiae

*This device has not been evaluated, cleared or approved for use by the FDA, and is not for sale in the U.S.

Our Advantages

GMR Technology

GMR technology offers more effective & efficient detection over traditional fluorescence methods

Lab-on-a-chip

Lab-on-a-chip technology allows for automated workflow with minimal manual requirements

Scalable

Modular & customizable design allows for scalability with future diagnostic applications

Highly Multiplexed

Proprietary GMR-based assay allows for 36-sensor array multiplexed target detection

Fast Turnaround

Zepto’s technology provides a turnaround time of < 90 minutes without foregoing quality

Highly Sensitive

GMR allows for higher signal to noise ratio compared to autofluorescence.

Highly Specific

High resolution melting differentiates non-specific bonding via thermal stress

Get In Touch

If you would like to learn more about our technology or would like to join our team, don’t be afraid to reach out! Zepto is always looking to incorporate promising new talent into our pool of dedicated & passionate innovators. Send us a message today!

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