Our Technology

Where Molecular Diagnostics meets Cutting Edge Lab-on-chip Technology

Zepto's Technology:

Unprecedented Turnaround Time w/ Pristine Sensitivity

Zepto utilizes Giant Magnetoresistance (GMR), a 2007 Nobel prize winning technological development to bring cutting edge diagnostic precision to the point of care.

*Not for sale in the U.S.

Sensitivity

Zepto's technology leverages GMR technology to achieve an astonishing molecular sensitivity of > 95%

Turnaround Time

Zepto's technology can achieve higher sensitivity with a turnaround time of
< 90 minutes

Multiplex

Zepto's innovations will allow for 36-plex uninterfered multiplex molecular detection

Invasive Fungal Infections in the U.S.

Zepto aims to disrupt current fungal diagnosis with a >99.5% sensitivity invasive fungal infection assay with results in less than 90min.

Every year, about 75,000 U.S. residents contract an invasive fungal infection (IFI). Globally, IFIs are responsible for an estimated 1.5 million deaths per year. In the U.S., 80% of antifungals are being misused due to ineffective and lengthy diagnostic tests. The current death rate from Fungal Infections is alarmingly high at around 35%-50%. This largely stems from the fact that current testing methods are both slow and lack sensitivity.

Turnaround Time

Blood cultures, the current diagnostic standard, takes anywhere from two to five days to return results.

Sensitivity

Blood culture IFI diagnostic testing only has a sensitivity of around 50%, nowhere near high enough to provide accurate results.

Issues With Commercial Fungal Tests:

The inability of current diagnostic practices to quickly and accurately identify invasive fungal infections has led to a patient mortality rate of between 35 – 50% and $4.5 billion hospital cost annually in the US. Accurate diagnostics within 12 hours reduces mortality to 11% however, blood culture, the current industry standard for diagnosis, takes two to five days and has a positive sensitivity of only 50%. Given the time constraints, doctors often start a shotgun of anti-fungal treatments, leading both to 80% of antifungals being misused and the rise in drug-resistant fungal strains1.

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IFIs in the U.S.1

Invasive Fungal Infections are one of the most prevalent and mistreated pathologies within the United States. Here are just some of the disturbing facts about patients suffering from IFIs in the U.S.

U.S. Invasive Fungal Infection Cases
75,000
Percentage of Antifungals Misused
80%
Current Mortality Rate
35-50%

1WHO fungal priority pathogens list to guide research, development and public health
action.; 2022.

Zepto’s Invasive Fungal Infection (IFI) Diagnostic Solution

Giant Magneto Resistance (GMR) technology enabled comprehensive & highly multiplexed molecular test that identifies >95% of common invasive fungal pathogens in the U.S.

*This device has not been evaluated, cleared or approved for use by the FDA, and is not for sale in the U.S.

Our Advantages

GMR Technology

GMR technology offers more effective & efficient detection over traditional fluorescence methods

Lab-on-a-chip

Lab-on-a-chip technology allows for automated workflow with minimal manual requirements

Scalable

Modular & customizable design allows for scalability with future diagnostic applications

Highly Multiplexed

Proprietary GMR-based assay allows for 36-sensor array multiplexed target detection

Fast Turnaround

Zepto’s technology provides a turnaround time of < 90 minutes without foregoing quality

Highly Sensitive

GMR allows for higher signal to noise ratio compared to autofluorescence.

Highly Specific

High resolution melting differentiates non-specific bonding via thermal stress

GMR Technology

GMR technology offers more effective & efficient detection over traditional fluorescence methods

Lab-on-a-chip

Lab-on-a-chip technology allows for automated workflow with minimal manual requirements

Scalable

Modular & customizable design allows for scalability with future diagnostic applications

Highly Multiplexed

Proprietary GMR-based assay allows for 36-sensor array multiplexed target detection

Fast Turnaround

Zepto’s technology provides a turnaround time of < 90 minutes without foregoing quality

Highly Sensitive

GMR allows for higher signal to noise ratio compared to autofluorescence.

Highly Specific

High resolution melting differentiates non-specific bonding via thermal stress

Get In Touch

If you would like to learn more about our technology or would like to join our team, don’t be afraid to reach out! Zepto is always looking to incorporate promising new talent into our pool of dedicated & passionate innovators. Send us a message today!